Percentages and distributions of teicoplanin- and vancomycin-resistant strains among coagulase-negative staphylococci
Author(s) -
F. W. Goldstein,
Anne Coutrot,
A Sieffer,
J. F. Acar
Publication year - 1990
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.34.5.899
Subject(s) - teicoplanin , microbiology and biotechnology , staphylococcus haemolyticus , vancomycin , agar dilution , coagulase , staphylococcus epidermidis , glycopeptide , micrococcaceae , agar dilution method , staphylococcus , biology , agar , staphylococcus aureus , antibacterial agent , bacteria , antibiotics , minimum inhibitory concentration , genetics
The activities of teicoplanin and vancomycin against 362 coagulase-negative staphylococci were determined by an agar dilution method. At the 4- and 32-micrograms/ml breakpoint levels of the National Committee for Clinical Laboratory Standards, 23.2% of the strains were intermediate and 1.7% were resistant to teicoplanin, in contrast to less than 0.3% intermediate to vancomycin. Resistant strains belonged to the species Staphylococcus epidermidis (74%) and S. haemolyticus (19%).
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