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Acute, rapidly progressive renal failure with simultaneous use of amphotericin B and pentamidine
Author(s) -
Diana Antoniskis,
Robert A. Larsen
Publication year - 1990
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.34.3.470
Subject(s) - pentamidine , pneumocystis carinii , amphotericin b , medicine , trimethoprim , pneumonia , sulfamethoxazole , antibiotics , gastroenterology , immunology , pneumocystis jirovecii , microbiology and biotechnology , antifungal , biology , dermatology
We report four cases of acute reversible renal failure in patients with acquired immune deficiency syndrome who received both amphotericin B (for systemic mycoses) and pentamidine isethionate (for Pneumocystis carinii pneumonia). The concurrent use of amphotericin B with either inhaled pentamidine or trimethoprim-sulfamethoxazole did not cause significant renal impairment.

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