Penetration of clindamycin, cefoxitin, and metronidazole into pelvic peritoneal fluid of women undergoing diagnostic laparoscopy | Zendy

S A Berger | Zendy; Michael J. Kupferminc | Zendy; Joseph B. Lessing | Zendy; A Gorea | Zendy; Iram Gull | Zendy; M. Reuben Peyser | Zendy

Open Access

Penetration of clindamycin, cefoxitin, and metronidazole into pelvic peritoneal fluid of women undergoing diagnostic laparoscopy

Author(s) -

S A Berger,

Michael J. Kupferminc,

Joseph B. Lessing,

A Gorea,

Iram Gull,

M. Reuben Peyser

Publication year - 1990

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.34.2.376

Subject(s) - cefoxitin , bacteroides fragilis , metronidazole , peritoneal fluid , medicine , clindamycin , cefotetan , antibiotics , bacteroides , laparoscopy , microbiology and biotechnology , gastroenterology , surgery , biology , bacteria , genetics , staphylococcus aureus

A single dose of clindamycin, cefoxitin, or metronidazole was administered to each of 30 women. The mean concentration of cefoxitin in pelvic fluid at 1 h exceeded those of the other two drugs (P less than 0.007). Cefoxitin concentrations were inferior to those of the other drugs when compared with the published MIC for 90% of Bacteroides fragilis strains.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research