Comparison of ofloxacin and ceftriaxone in the treatment of uncomplicated gonorrhea caused by penicillinase-producing and non-penicillinase-producing strains | Zendy

Jean Covino | Zendy; Marinella Cummings | Zendy; Barry L Smith | Zendy; S Beneş | Zendy; KENNETH DRAFT | Zendy; William M. McCormack | Zendy

Open Access

Comparison of ofloxacin and ceftriaxone in the treatment of uncomplicated gonorrhea caused by penicillinase-producing and non-penicillinase-producing strains

Author(s) -

Jean Covino,

Marinella Cummings,

Barry L Smith,

S Beneş,

KENNETH DRAFT,

William M. McCormack

Publication year - 1990

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.34.1.148

Subject(s) - ceftriaxone , ofloxacin , gonorrhea , neisseria gonorrhoeae , medicine , microbiology and biotechnology , gastroenterology , beta lactamase , intramuscular injection , antibiotics , pharmacology , biology , virology , ciprofloxacin , escherichia coli , biochemistry , human immunodeficiency virus (hiv) , gene

Eighty-nine patients with uncomplicated gonorrhea, including 31 patients (34.8%) infected with penicillinase-producing strains of Neisseria gonorrhoeae, were treated with oral ofloxacin (single 400-mg dose) or intramuscular ceftriaxone (250-mg dose). All 47 patients who received ofloxacin and 41 of 42 patients who received ceftriaxone were cured.

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