Penicillin-binding protein 2 is required for induction of the Citrobacter freundii class I chromosomal beta-lactamase in Escherichia coli | Zendy

B Oliva | Zendy; Peter M. Bennett | Zendy; I. Chopra | Zendy

Open Access

Penicillin-binding protein 2 is required for induction of the Citrobacter freundii class I chromosomal beta-lactamase in Escherichia coli

Author(s) -

B Oliva,

Peter M. Bennett,

I. Chopra

Publication year - 1989

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.33.7.1116

Subject(s) - citrobacter freundii , escherichia coli , penicillin binding proteins , citrobacter , enterobacteriaceae , mutant , penicillin , microbiology and biotechnology , biology , beta lactamase , sos response , gene , antibiotics , biochemistry

Involvement of Escherichia coli penicillin-binding proteins (PBPs) in induction of the cloned ampC Citrobacter freundii beta-lactamase by 6-aminopenicillanic acid was investigated. The enzyme was not inducible at 42 degrees C in a mutant thermosensitive for expression of PBP 2. The results imply that PBP 2 is involved in the process leading to induction of ampC.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research