Quinolone resistance in clinical isolates of Serratia marcescens | Zendy

Kazuo Fujimaki | Zendy; Tatsuya Fujii | Zendy; Hiroshi Aoyama | Zendy; Kenichi Sato | Zendy; Yasushi Inoue | Zendy; Manabu Inoue | Zendy; S Mitsuhashi | Zendy

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Quinolone resistance in clinical isolates of Serratia marcescens

Author(s) -

Kazuo Fujimaki,

Tatsuya Fujii,

Hiroshi Aoyama,

Kenichi Sato,

Yasushi Inoue,

Manabu Inoue,

S Mitsuhashi

Publication year - 1989

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.33.5.785

Subject(s) - serratia marcescens , dna gyrase , norfloxacin , quinolone , microbiology and biotechnology , ofloxacin , biology , antibacterial agent , nalidixic acid , serratia , bacteria , antibiotics , ciprofloxacin , escherichia coli , genetics , pseudomonas , gene

The uptakes of norfloxacin by quinolone-resistant and -susceptible strains of Serratia marcescens were almost the same and 50% inhibitory concentrations for DNA gyrase and the MICs of quinolones were correlated, suggesting that DNA gyrase alterations are the basis of quinolone resistance.

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