Widespread quinolone resistance among methicillin-resistant Staphylococcus aureus isolates in a general hospital | Zendy

Itamar Shalit | Zendy; S A Berger | Zendy; A Gorea | Zendy; H Frimerman | Zendy

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Widespread quinolone resistance among methicillin-resistant Staphylococcus aureus isolates in a general hospital

Author(s) -

Itamar Shalit,

S A Berger,

A Gorea,

H Frimerman

Publication year - 1989

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.33.4.593

Subject(s) - staphylococcus aureus , microbiology and biotechnology , ciprofloxacin , ofloxacin , quinolone , methicillin resistant staphylococcus aureus , micrococcaceae , bacteriophage , meticillin , biology , antibacterial agent , antibiotics , medicine , bacteria , escherichia coli , biochemistry , genetics , gene

Ofloxacin and ciprofloxacin resistance (MIC, greater than 4 micrograms/ml) was encountered in 45 of 50 clinical isolates of methicillin-resistant Staphylococcus aureus. None of 20 methicillin-susceptible strains was resistant to the quinolones (P less than 10(-6). Quinolone-susceptible and -resistant isolates did not differ with respect to culture source or bacteriophage type. The future usefulness of quinolones for S. aureus infection may be limited.

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