In vitro activities of the newer beta-lactam and quinolone antimicrobial agents against Pseudomonas pseudomallei
Author(s) -
Leslie R. Ashdown
Publication year - 1988
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.32.9.1435
Subject(s) - ticarcillin , piperacillin , cefotaxime , ceftazidime , microbiology and biotechnology , clavulanic acid , imipenem , ciprofloxacin , azlocillin , antimicrobial , norfloxacin , pseudomonas , quinolone , antibacterial agent , biology , amoxicillin , antibiotics , pseudomonas aeruginosa , bacteria , antibiotic resistance , genetics
Imipenem was highly active and bactericidal against all 100 strains of Pseudomonas pseudomallei tested, followed in activity by piperacillin, carumonam, ceftazidime, cefotaxime, and ceftriaxone. The addition of clavulanic acid significantly increased the activities of both amoxicillin and ticarcillin. Ciprofloxacin and norfloxacin showed poor activity against test strains.
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