Effect of ciprofloxacin on carrier rate of Neisseria meningitidis in army recruits in Finland
Author(s) -
O V Renkonen,
Kaarina Sivonen,
R. Visakorpi
Publication year - 1987
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.31.6.962
Subject(s) - neisseria meningitidis , ciprofloxacin , carriage , neisseriaceae , microbiology and biotechnology , medicine , placebo , colonization , neisseria , meningococcal vaccine , meningococcal disease , antibiotics , biology , bacteria , genetics , alternative medicine , pathology
The efficacy of ciprofloxacin in eradicating pharyngeal colonization of Neisseria meningitidis was studied among army recruits in Finland. Ciprofloxacin (250 mg) or placebo was given twice a day for 2 days to 118 meningococcal carriers. Meningococcal carriage was eradicated in 96% of subjects given ciprofloxacin and in 13% of those given placebos.
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