Open AccessMore than one DNA sequence encodes the 2''-O-adenylyltransferase phenotype
Author(s) -
S C Lee,
P. Patrick Cleary,
Dale N. Gerding
Publication year - 1987
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.31.4.667
Subject(s) - plasmid , biology , phenotype , gene , genetics , encode , ant , dna sequencing , dna , dna–dna hybridization , microbiology and biotechnology , ecology
Biochemical and phenotypic assays indicate that three enterobacterial R plasmids isolated in a single hospital encode 2''-O-adenylyltransferase [ANT(2'')], and an ANT(2'')-specific probe was developed from one plasmid. Southern hybridization revealed the three plasmids to be unrelated and, further, showed their ANT(2'')-encoding genes to be different.