In vitro activity of Ro 15-8074, Ro 19-5247, A-56268, and roxithromycin (RU 28965) against Neisseria gonorrhoeae and Chlamydia trachomatis
Author(s) -
W R Bowie,
Carol E. Shaw,
Deng Chan,
W. A. P. Black
Publication year - 1987
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.31.3.470
Subject(s) - neisseria gonorrhoeae , chlamydia trachomatis , roxithromycin , microbiology and biotechnology , penicillin , neisseriaceae , cephalosporin , in vitro , erythromycin , neisseria , medicine , biology , virology , antibiotics , bacteria , biochemistry , genetics
In vitro Ro 15-8074 and Ro 19-5247 (T2525), two new oral cephalosporins, were active against 410 penicillin-susceptible and -resistant isolates of Neisseria gonorrhoeae. Two new macrolides, A-56268 and to a lesser extent roxithromycin (RU 28965), were active against Chlamydia trachomatis. A-56268 had activity against N. gonorrhoeae similar to that of erythromycin.
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