Single-dose ceftriaxone for chancroid
Author(s) -
M. Ian Bowmer,
H Nsanze,
L J D'Costa,
Joe Dylewski,
L Fransen,
Peter Piot,
Allan Ronald
Publication year - 1987
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.31.1.67
Subject(s) - haemophilus ducreyi , chancroid , ceftriaxone , medicine , antibiotics , intramuscular injection , pasteurellaceae , antibacterial agent , sexually transmitted disease , syphilis , microbiology and biotechnology , virology , haemophilus influenzae , biology , human immunodeficiency virus (hiv)
Men with genital ulcers that were culture positive for Haemophilus ducreyi were treated with intramuscular ceftriaxone and randomized to three different dose regimens. All but 1 of 50 men treated with 1 g of intramuscular ceftriaxone were cured. Similarly, 0.5 and 0.25 g cured 43 of 44 men and 37 of 38 men, respectively. A single dose of 250 mg of intramuscular ceftriaxone is an effective treatment for chancroid.
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