Open AccessAllium sativum (garlic) inhibits lipid synthesis by Candida albicans
Author(s) -
Moses A. Adetumbi,
George T. Javor,
Benjamin H.S. Lau
Publication year - 1986
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.30.3.499
Subject(s) - allium sativum , candida albicans , nucleic acid , biochemistry , chemistry , microbiology and biotechnology , biology , botany
The effect of aqueous garlic extract on the macromolecular synthesis of Candida albicans was studied. Protein and nucleic acid syntheses were inhibited to the same extent as growth, but lipid synthesis was completely arrested. Blockage of lipid synthesis is likely an important component of the anticandidal activity of garlic.
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