Comparative clinical efficacy of single oral doses of cefuroxime axetil and amoxicillin in uncomplicated gonococcal infections | Zendy

I. W. Fong | Zendy; W Linton | Zendy; M Simbul | Zendy; N A Hinton | Zendy

Open Access

Comparative clinical efficacy of single oral doses of cefuroxime axetil and amoxicillin in uncomplicated gonococcal infections

Author(s) -

I. W. Fong,

W Linton,

M Simbul,

N A Hinton

Publication year - 1986

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.30.2.321

Subject(s) - cefuroxime , amoxicillin , gonorrhea , medicine , probenecid , antibacterial agent , antibiotics , gastroenterology , microbiology and biotechnology , immunology , biology , human immunodeficiency virus (hiv)

Cefuroxime axetil (1.5 g) was compared with amoxicillin (3 g), both given as a single oral dose combined with probenecid (1 g) for the treatment of uncomplicated gonorrhea. Of 60 evaluable patients receiving amoxicillin, 55 (91.7%) were cured, whereas 55 (96.5%) of the 57 patients receiving cefuroxime axetil were cured (P greater than 0.1). Both drugs were well tolerated.

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