Open AccessFailure of 1-β- d -Ribofuranosyl-1,2,4-Triazole-3-Carboxamide (Virazole, ICN 1229) to Stimulate Interferon
Author(s) -
Lois B. Allen,
John H. Huffman,
Robert W. Sidwell
Publication year - 1973
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.3.4.534
Subject(s) - interferon , medicine , virology , pharmacology , microbiology and biotechnology , biology
In cultured cells, Virazole failed to stimulate either interferon or a cellular resistance which continued in its absence. Serum from Virazole-treated mice likewise contained no demonstrable interferon.
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