Dissemination of the tetM tetracycline resistance determinant to Ureaplasma urealyticum
Author(s) -
Marilyn C. Roberts,
G E Kenny
Publication year - 1986
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.29.2.350
Subject(s) - ureaplasma urealyticum , tetracycline , ureaplasma , biology , microbiology and biotechnology , serotype , mollicutes , mycoplasmataceae , gel electrophoresis , southern blot , blot , antibacterial agent , homologous chromosome , dna , antibiotics , genetics , mycoplasma , gene
Ureaplasma urealyticum is an organism considered susceptible to tetracycline. Ten tetracycline-resistant (Tcr) clinical isolates and Tcr serotype 9 were examined. All contained DNA sequences homologous to the streptococcal determinant tetM. They differed from each other on sodium dodecyl sulfate-polyacrylamide gel electrophoresis, Southern blots, and immunoblots and appeared to represent different strains.
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