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Mechanism of resistance to silver ions in Klebsiella pneumoniae
Author(s) -
Preetinder Kaur,
D. V. Vadehra
Publication year - 1986
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.29.1.165
Subject(s) - klebsiella pneumoniae , strain (injury) , microbiology and biotechnology , spheroplast , bacteria , klebsiella , biology , chemistry , escherichia coli , biochemistry , gene , genetics , anatomy
The uptake of silver by an experimentally derived silver-resistant Klebsiella pneumoniae strain was three to four times lower than the uptake by a susceptible strain. Spheroplasts of the two strains showed no difference in uptake. AgNO3 at a concentration of 40 micrograms/ml decreased the succinate dehydrogenase activity in susceptible and resistant strains by 100 and 18%, respectively. More than one resistance mechanism may be involved.

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