In vitro activity of carumonam | Zendy

Robert J. Fass | Zendy; V L Helsel | Zendy

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In vitro activity of carumonam

Author(s) -

Robert J. Fass,

V L Helsel

Publication year - 1985

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.28.6.834

Subject(s) - piperacillin , microbiology and biotechnology , anaerobic bacteria , clindamycin , antimicrobial , bacteria , biology , chemistry , antibiotics , genetics , pseudomonas aeruginosa

The in vitro activities of carumonam and eight comparative antimicrobial agents were studied. MICs of carumonam were less than or equal to 0.5 microgram/ml for 91% of members of the family Enterobacteriaceae and less than or equal to 16 micrograms/ml for 88% of nonfermenters; gram-positive cocci and anaerobic bacteria were resistant. Combinations of carumonam with piperacillin, nafcillin, or clindamycin were usually indifferent, although synergy between carumonam and piperacillin was observed with 20 (13%) of 155 strains.

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