Development of plasmid-mediated resistance in Vibrio cholerae during treatment with trimethoprim-sulfamethoxazole | Zendy

M.J. Dupont | Zendy; Michèle Jouvenot | Zendy; G. Couetdic | Zendy; Y Michel-Briand | Zendy

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Development of plasmid-mediated resistance in Vibrio cholerae during treatment with trimethoprim-sulfamethoxazole

Author(s) -

M.J. Dupont,

Michèle Jouvenot,

G. Couetdic,

Y Michel-Briand

Publication year - 1985

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.27.2.280

Subject(s) - vibrio cholerae , trimethoprim , microbiology and biotechnology , plasmid , sulfamethoxazole , ampicillin , chloramphenicol , el tor , biology , vibrionaceae , amp resistance , antibiotics , bacteria , genetics , gene

The persistence of Vibrio cholerae, biotype el tor, in a patient treated with trimethoprim-sulfamethoxazole was due to the acquisition of a conjugative resistance plasmid. The plasmid, with a molecular size of 72 megadaltons, belonged to incompatibility group 6-C and conferred resistance to ampicillin, chloramphenicol, sulfonamide, and trimethoprim.

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