Effect of aztreonam on throat and stool flora of cancer patients | Zendy

Paula G. Jones | Zendy; Gerald P. Bodey | Zendy; Edward A. Swabb | Zendy; B Rosenbaum | Zendy

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Effect of aztreonam on throat and stool flora of cancer patients

Author(s) -

Paula G. Jones,

Gerald P. Bodey,

Edward A. Swabb,

B Rosenbaum

Publication year - 1984

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.26.6.941

Subject(s) - aztreonam , throat , medicine , microbiology and biotechnology , flora (microbiology) , dosing , gastroenterology , antibiotics , biology , surgery , bacteria , genetics , antibiotic resistance , imipenem

Eighteen patients with hematological malignancies received aztreonam in one of two dosing regimens, 1 or 2 g every 8 h for a total of 7 to 9 days. Throat and stool cultures were obtained before and during treatment with aztreonam. Aztreonam had little effect on the predominant throat flora. In contrast, facultatively anaerobic gram-negative bacilli were markedly decreased in stools during the administration of aztreonam. Strict anaerobes in the stool were variably affected by aztreonam.

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