In vitro antimicrobial susceptibilities of penicillinase-producing and non-penicillinase-producing strains of Neisseria gonorrhoeae isolated in Durban, South Africa | Zendy

Yacoob Coovadia | Zendy; U Ramsaroop | Zendy

Open Access

In vitro antimicrobial susceptibilities of penicillinase-producing and non-penicillinase-producing strains of Neisseria gonorrhoeae isolated in Durban, South Africa

Author(s) -

Yacoob Coovadia,

U Ramsaroop

Publication year - 1984

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.26.5.770

Subject(s) - cefotaxime , neisseria gonorrhoeae , cephalosporin , microbiology and biotechnology , ceftriaxone , clavulanic acid , ceftazidime , antimicrobial , beta lactamase , antibiotics , biology , amoxicillin , bacteria , escherichia coli , biochemistry , genetics , gene , pseudomonas aeruginosa

The in vitro susceptibilities of 22 penicillinase-producing and 32 non-penicillinase-producing strains of Neisseria gonorrhoeae to 13 antimicrobial agents, including the new semisynthetic penicillins and cephalosporins, are reported. Ceftriaxone, ceftazidime, and cefotaxime were the most active agents tested; none of them had an MIC of greater than 0.03 micrograms/ml. Amoxycillin plus clavulanic acid and temocillin also showed good activity against both strains of gonococci.

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