Susceptibility of Bordetella pertussis to cephalosporin derivatives and imipenem | Zendy

Robert M. Bannatyne | Zendy; R Cheung | Zendy

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Susceptibility of Bordetella pertussis to cephalosporin derivatives and imipenem

Author(s) -

Robert M. Bannatyne,

R Cheung

Publication year - 1984

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.26.4.604

Subject(s) - imipenem , cefsulodin , cefoperazone , cephalosporin , bordetella pertussis , microbiology and biotechnology , ceftriaxone , antibacterial agent , chemistry , antibiotics , medicine , biology , ceftazidime , bacteria , pseudomonas aeruginosa , antibiotic resistance , genetics

The in vitro activities of 16 cephalosporin derivatives and imipenem against 60 strains of Bordetella pertussis were examined. Cefoperazone, imipenem, and ceftriaxone were the most active, with MICs that inhibited 90% of the strains of 0.006, 0.05, and 0.1 microgram/ml, respectively. Cephalexin, cephradine, and cefsulodin were the least active, with MICs of 25 to 125 micrograms/ml. The remainder of the agents demonstrated intermediate activity.

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