Open AccessIn vitro comparison of amifloxacin and six other antibiotics against aminoglycoside-resistant Pseudomonas aeruginosa
Author(s) -
Kenneth D. Thompson,
J. Paul O'Keefe,
Walter A. Tatarowicz
Publication year - 1984
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.26.2.275
Subject(s) - aminoglycoside , aztreonam , antibiotics , pseudomonas aeruginosa , cefotaxime , gentamicin , microbiology and biotechnology , ampicillin , in vitro , biology , chemistry , bacteria , antibiotic resistance , imipenem , biochemistry , genetics
The in vitro activity of the synthetic fluoroquinolone amifloxacin was compared with those of six other antibiotics: ampicillin, aztreonam, cefotaxime, cephalexin, cinoxacin, and gentamicin. Amifloxacin had the lowest 50% MIC of any of the antibiotics tested against aminoglycoside-resistant Pseudomonas aeruginosa, 4 micrograms/ml.