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Sulfamethoxazole-trimethoprim-resistant Shigella flexneri in northeastern Brazil
Author(s) -
Karen M. Tiemens,
P L Shipley,
Rossana Correia,
David S. Shields,
Richard L. Guerrant
Publication year - 1984
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.25.5.653
Subject(s) - shigella flexneri , trimethoprim , sulfamethoxazole , microbiology and biotechnology , shigella , diarrhea , escherichia coli , enterobacteriaceae , biology , shigellosis , plasmid , virology , medicine , antibiotics , genetics , gene , dna
In contrast to prior experience in northeastern Brazil, three of four Shigella flexneri strains recently isolated from patients with acute inflammatory diarrhea in this setting were found to be resistant to sulfamethoxazole-trimethoprim. The resistant strains contained large, different plasmids, two of which were transferred with sulfamethoxazole-trimethoprim resistance to Escherichia coli K-12 recipient strains.

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