Open AccessSynergistic antiviral effects of antiherpes compounds and human leukocyte interferon on varicella-zoster virus in vitro
Author(s) -
Masanori Baba,
Masaihiko Ito,
Shirô Shigeta,
Erik De Clercq
Publication year - 1984
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.25.4.515
Subject(s) - in vitro , varicella zoster virus , virus , virology , interferon , biology , chemistry , pharmacology , biochemistry
The four antiherpes compounds acyclovir, adenine arabinoside, bromovinyldeoxyuridine, and phosphonoformic acid showed an additive to synergistic effect with human leukocyte interferon in inhibiting focus formation by three different strains of varicella-zoster virus in human embryonic fibroblasts.
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