Open AccessIn vitro activity of midecamycin, a new macrolide antibiotic
Author(s) -
H. C. Neu
Publication year - 1983
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.24.3.443
Subject(s) - erythromycin , microbiology and biotechnology , antibiotics , macrolide antibiotics , listeria , bacteria , antibacterial agent , haemophilus , biology , in vitro , listeria monocytogenes , biochemistry , genetics
Midecamycin, an acetoxy-substituted macrolide antibiotic, was tested against gram-positive and gram-negative bacteria. It inhibited the majority of streptococci, staphylococci, and strains of Haemophilus and Listeria at concentrations of less than 3.1 micrograms/ml. It was less active than erythromycin, and it failed to inhibit erythromycin-resistant isolates.
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