Minimal inhibitory concentrations of lucknomycin, a new polyenic derivative, for Candida and Aspergillus spp | Zendy

Jorge Martı́nez | Zendy; Josep M. Torres-Rodrı́guez | Zendy; M Rosés-Codinachs | Zendy; M Amaral-Olivera | Zendy

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Minimal inhibitory concentrations of lucknomycin, a new polyenic derivative, for Candida and Aspergillus spp

Author(s) -

Jorge Martı́nez,

Josep M. Torres-Rodrı́guez,

M Rosés-Codinachs,

M Amaral-Olivera

Publication year - 1983

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.24.1.132

Subject(s) - aspergillus fumigatus , candida albicans , aspergillus niger , minimum inhibitory concentration , microbiology and biotechnology , fungi imperfecti , aspergillus , candida tropicalis , biology , antibiotics , biochemistry

The minimal inhibitory concentrations (MICs) of lucknomycin, a new polyenic derivative, were determined for 101 clinical isolates of Candida, 38 clinical or environmental strains of Aspergillus fumigatus, and 30 isolates of A. niger. The most susceptible species were Candida albicans and Candida tropicalis (mean MIC, 0.4 micrograms/ml). Aspergillus spp. were less susceptible, with mean MICs of 0.60 micrograms/ml for Aspergillus niger and 9.2 micrograms/ml for Aspergillus fumigatus.

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