Open AccessMoxalactam treatment of anaerobic infections in cancer patients
Author(s) -
Hjalmar Lagast,
F. Meunier-Carpentier,
Jean Klášterský
Publication year - 1982
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.22.4.604
Subject(s) - moxalactam , anaerobic exercise , medicine , microbiology and biotechnology , biology , antibiotics , cephalosporin , physiology
Of 30 patients with predominantly anaerobic localized infections superimposed on chronic tissue damage related to trauma, ischemia, or tumor, 22 (73%) responded satisfactorily to moxalactam therapy. Moxalactam-resistant anaerobic pathogens emerged in two patients and were responsible for treatment failure. In six patients, two of whom also acquired resistant anaerobic pathogens, isolation of moxalactam-resistant aerobic pathogens increased during therapy.