Comparative effects of moxalactam and gentamicin on human polymorphonuclear leukocyte functions | Zendy

Carmen Burgaleta | Zendy; J Martínez-Beltrán | Zendy; Emilio Bouza | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Comparative effects of moxalactam and gentamicin on human polymorphonuclear leukocyte functions

Author(s) -

Carmen Burgaleta,

J Martínez-Beltrán,

Emilio Bouza

Publication year - 1982

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.21.5.718

Subject(s) - moxalactam , gentamicin , incubation , chemotaxis , microbiology and biotechnology , in vitro , polymorphonuclear leukocyte , aminoglycoside , incubation period , immunology , antibiotics , medicine , biology , chemistry , pharmacology , cephalosporin , biochemistry , receptor

The in vitro effects of moxalactam and gentamicin on chemotactic, phagocytic, and microbicidal activities of human polymorphonuclear leukocytes have been studied. Incubation of cells with moxalactam (25 to 400 micrograms/ml) resulted in a 10 to 15% inhibition of leukocyte chemotaxis (P less than or equal to 0.10). Incubation of cells with gentamicin (5 to 40 micrograms/ml) inhibited chemotaxis more than 50% (P less than or equal to 0.50). Neither moxalactam nor gentamicin had any effect on phagocytic or microbicidal capacities of leukocytes.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research