Comparative in vitro bactericidal activity of cefonicid, ceftizoxime, and penicillin against group B streptococci | Zendy

A S Bayer | Zendy; Joan O. Morrison | Zendy; K S Kim | Zendy

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Comparative in vitro bactericidal activity of cefonicid, ceftizoxime, and penicillin against group B streptococci

Author(s) -

A S Bayer,

Joan O. Morrison,

K S Kim

Publication year - 1982

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.21.2.344

Subject(s) - ceftizoxime , penicillin , microbiology and biotechnology , cephalosporin , minimum inhibitory concentration , cefamandole , cefotaxime , chemistry , antibacterial agent , antibiotics , biology

The minimal inhibitory and bactericidal concentrations for 108 group B streptococcal strains were determined for two new cephalosporins, cefonicid and ceftizoxime, and compared to those of penicillin G. Penicillin G was the most active inhibitory and bactericidal agent. Ceftizoxime was a significantly more active inhibitory and bactericidal agent than cefonicid (P less than 0.0005, P less than 0.025, respectively.

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