Cefaclor pharmacokinetic parameters: serum concentrations determined by a new high-performance liquid chromatographic technique | Zendy

John C. Rotschafer | Zendy; Kent Crossley | Zendy; Timothy S. Lesar | Zendy; Darwin E. Zaske | Zendy; Kenneth W. Miller | Zendy

Open Access

Cefaclor pharmacokinetic parameters: serum concentrations determined by a new high-performance liquid chromatographic technique

Author(s) -

John C. Rotschafer,

Kent Crossley,

Timothy S. Lesar,

Darwin E. Zaske,

Kenneth W. Miller

Publication year - 1982

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.21.1.170

Subject(s) - cefaclor , pharmacokinetics , chromatography , oral administration , serum concentration , high performance liquid chromatography , chemistry , antibacterial agent , pharmacology , medicine , cephalosporin , antibiotics , biochemistry

Pharmacokinetic parameters of cefaclor were studied in eight patients after an oral dose of 250 mg. Serum samples were obtained before and on 19 occasions after oral administration. Cefaclor serum concentrations were determined by a new high-performance liquid chromatographic technique.

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