Open AccessBioavailability of Bacampicillin and Talampicillin, Two Oral Prodrugs of Ampicillin
Author(s) -
Jan Sjövall,
L. Magni,
E. Vinnars
Publication year - 1981
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.20.6.837
Subject(s) - bioavailability , prodrug , ampicillin , chemistry , pharmacology , antibiotics , cephalosporin , oral administration , medicine , biochemistry
A 200-mg amount of bacampicillin showed a significantly higher relative extent of bioavailability than did a 250-mg amount of talampicillin, possibly due to their different stability in the digestive juices.
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