Open AccessConjugal transfer of an R-plasmid in Pasteurella multocida
Author(s) -
Dwight C. Hirsh,
Liliane Martin,
Keith R. Rhoades
Publication year - 1981
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.20.3.415
Subject(s) - pasteurella multocida , fowl cholera , plasmid , microbiology and biotechnology , streptomycin , biology , escherichia coli , strain (injury) , pasteurella , gene , virology , bacteria , antibiotics , genetics , anatomy
A strain of Pasteurella multocida isolated from turkeys during an outbreak of septicemic disease (fowl cholera) was shown to possess the ability to transfer streptomycin and sulphadiazine resistance to P. multocida and to Escherichia coli by conjugation. The genes necessary for the transfer of the resistance genes appeared to be associated with a plasmid of molecular weight 28.5 x 10(6). The resistance genes were shown to be associated with a second plasmid of molecular weight 7.2 x 10(6).