Susceptibility of Multiply Antibiotic-Resistant Pneumococci to the New Beta-Lactam Drugs and Rosaramicin | Zendy

Sheldon H. Landesman | Zendy; Marinella Cummings | Zendy; Andrea Gruarin | Zendy; Harriet P. Bernheimer | Zendy

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Susceptibility of Multiply Antibiotic-Resistant Pneumococci to the New Beta-Lactam Drugs and Rosaramicin

Author(s) -

Sheldon H. Landesman,

Marinella Cummings,

Andrea Gruarin,

Harriet P. Bernheimer

Publication year - 1981

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.19.4.675

Subject(s) - penicillin , antibiotics , beta lactam , erythromycin , lactam , microbiology and biotechnology , streptococcus pneumoniae , cephalosporin , medicine , biology , chemistry , stereochemistry

Eight new beta-lactam antibiotics and rosaramicin were tested for their activity against penicillin-susceptible and multiply resistant pneumococci. All of the beta-lactam drugs were 50- to 150-fold less active against the drug-resistant pneumococci when compared with their activity against penicillin-susceptible pneumococci. Rosaramicin activity was similar to that of erythromycin.

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