Open AccessAntimicrobial susceptibility of Campylobacter jejuni and Campylobacter fetus subsp. fetus to eight cephalosporins with special reference to species differentiation
Author(s) -
Mohamed A. Karmali,
S De Grandis,
Peter D. Fleming
Publication year - 1980
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.18.6.948
Subject(s) - campylobacter fetus , cephaloridine , cefoxitin , cephalosporin , cefotaxime , microbiology and biotechnology , campylobacter , nalidixic acid , agar dilution , biology , cefamandole , campylobacter coli , antimicrobial , campylobacter jejuni , cefazolin , antibiotics , ciprofloxacin , bacteria , minimum inhibitory concentration , genetics , staphylococcus aureus
Agar dilution antimicrobial susceptibility testing showed that Campylobacter jejuni was significantly more resistant than Campylobacter fetus subsp. fetus (intestinalis) to cephalosporin C, cephaloridine, cephalothin, cefazolin, and cefamandole. No species differences in susceptibility were noted with cephalexin, cefotaxime, and cefoxitin. Rapid species differentiation on the basis of an antibiogram could be achieved with the disk diffusion method. C jejuni failed to produce a zone of inhibition around a 30-microgram cephalothin disk but produced a significant zone around a 30-microgram nalidixic acid disk. C. fetus subsp. fetus (intestinalis) produced exactly the reverse pattern.