In vitro susceptibility of Mycobacterium marinum to eight antimicrobial agents | Zendy

William J. Sanders | Zendy; E WOLINSKY | Zendy

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In vitro susceptibility of Mycobacterium marinum to eight antimicrobial agents

Author(s) -

William J. Sanders,

E WOLINSKY

Publication year - 1980

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.18.4.529

Subject(s) - mycobacterium marinum , amikacin , minocycline , antimicrobial , gentamicin , microbiology and biotechnology , kanamycin , tetracycline , agar dilution , doxycycline , erythromycin , minimum inhibitory concentration , trimethoprim , antibacterial agent , aminoglycoside , antibiotics , biology , mycobacterium , bacteria , genetics

The in vitro susceptibilities of 16 Mycobacterium marinum strains to eight antimicrobial agents were determined by the agar dilution technique. The most active drugs were amikacin and kanamycin. Tetracycline, doxycycline, and minocycline were inhibitory, predominantly at concentrations slightly below the expected blood and tissue levels. Trimethoprim-sulfamethoxazole and erythromycin demonstrated activity only at concentrations greater than those usually attained in serum and tissues. Gentamicin was relatively inactive.

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