Effects of cerulenin on antibiotic-induced lysis of streptococcus faecalis (S. faecium) | Zendy

L Daneo-Moore | Zendy; Paul Bourbeau | Zendy; Robert A. Weinstein | Zendy; Daniel D. Carson | Zendy

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Effects of cerulenin on antibiotic-induced lysis of streptococcus faecalis (S. faecium)

Author(s) -

L Daneo-Moore,

Paul Bourbeau,

Robert A. Weinstein,

Daniel D. Carson

Publication year - 1979

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.16.6.858

Subject(s) - microbiology and biotechnology , lysis , bacitracin , antibiotics , fosfomycin , penicillin , vancomycin , cerulenin , antibacterial agent , cycloserine , bacteria , biology , chemistry , immunology , biochemistry , staphylococcus aureus , enzyme , genetics , fatty acid synthase

Addition of the antibiotic cerulenin to cultures lowered the minimal effective concentration of penicillin G or methicillin required to produce bacterial lysis and killing. This effect was most pronounced at subinhibitory antibiotic concentrations. Cerulenin had no significant effects on lysis or killing induced in the presence of D-cycloserine, fosfomycin, bacitracin, or vancomycin.

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