Open AccessChlorhexidine as an effective agent against Chlamydia trachomatis in vitro and in vivo
Author(s) -
Ian T. Nisbet,
Doris M. Graham,
P E Spicer,
G J Tibbs
Publication year - 1979
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.16.6.855
Subject(s) - chlorhexidine , chlamydia trachomatis , trachoma , in vivo , in vitro , antibacterial agent , chlamydiaceae , medicine , pharmacology , chlamydia , doxycycline , microbiology and biotechnology , antibiotics , chemistry , biology , dentistry , immunology , pathology , biochemistry
In a small field trial, chlorhexidine (50 micrograms/ml) was as effective against clinical trachoma as topical tetracyclines or oral co-trimoxazole; in vitro, 2.5 micrograms/ml was chlamydicidal.
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