Open AccessIn Vitro Evaluation of Seven Cationic Detergents as Antiplaque Agents
Author(s) -
Jason M. Tanzer,
Andrew M. Slee,
B. Kamay,
Eleanor R. Scheer
Publication year - 1979
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.15.3.408
Subject(s) - streptococcus mutans , actinomyces naeslundii , actinomyces , chlorhexidine , microbiology and biotechnology , dental plaque , in vitro , chemistry , in vivo , bacteria , dentistry , biology , medicine , biochemistry , genetics
The bactericidal efficacy of seven cationic detergents was studied in vitro against intact performed plaques of representative strains of four oral dental plaque-forming microorganisms:Streptococcus mutans, Streptococcus sanguis, Actinomyces viscosus , andActinomyces naeslundii . Both absolute (plaque bactericidal index) and relative (chlorhexidine coefficient) indexes of antiplaque activity were established. Only cetyltrimethylammonium bromide was more efficacious than the reference agent, the bisbiguanide chlorhexidine, for the apparently more potent tooth-adherent cariogenic and periodontopathic elements, respectively, of the in vivo plaque microflora,S. mutans andA. viscosus .