Open AccessPatient Variables Associated with Penicillin Resistance in Neisseria gonorrhoeae
Author(s) -
Clyde Thornsberry,
Harold W. Jaffe,
Gladys H. Reynolds,
Akbar A. Zaidi,
Paul J. Wiesner
Publication year - 1978
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.14.3.327
Subject(s) - gonorrhea , neisseria gonorrhoeae , penicillin , urethritis , microbiology and biotechnology , medicine , antibiotic resistance , neisseriaceae , antimicrobial , drug resistance , antibiotics , biology , immunology , human immunodeficiency virus (hiv)
In an ongoing cooperative study of uncomplicated genital gonorrhea within the United States, 6,735 pretreatment gonococcal isolates were tested for their in vitro resistance to penicillin. By using a regression analysis technique, we examined 99 patient-associated variables which might be associated with penicillin resistance of the isolates. Patients were most likely to have relatively resistant isolates if they were black, had used antimicrobial agents within 2 weeks of treatment for gonorrhea, or were men with symptomatic urethritis.