Pharmacokinetics of Cefamandole in Infants and Children | Zendy

Stuart H. Walker | Zendy; Victoria P. Gahol | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Pharmacokinetics of Cefamandole in Infants and Children

Author(s) -

Stuart H. Walker,

Victoria P. Gahol

Publication year - 1978

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.14.3.315

Subject(s) - cefamandole , pharmacokinetics , dosing , medicine , minimum inhibitory concentration , serum concentration , pediatrics , cephalosporin , physiology , anesthesia , pharmacology , antibiotics , chemistry , biochemistry

In infants less than 3 months of age, the serum concentration of cefamandole during therapy was higher and more prolonged than that in children older than 1 year. A dosage of 37 mg/kg administered intravenously at 6-h intervals provided a serum concentration in excess of the minimum inhibitory concentrations of common bacterial pathogens for 4 h, and in young infants for 5 h, after dosing.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research