Open AccessEfficacy of 5,6-Dihydro-5-Azathymidine Against Cutaneous Herpes Simplex Virus in Hairless Mice
Author(s) -
Gerald E. Underwood,
Sheldon D. Weed
Publication year - 1977
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.11.4.765
Subject(s) - hairless , herpes simplex virus , virology , medicine , virus , dermatology , biology , genetics
5,6-Dihydro-5-azathymidine, administered subcutaneously, was active both prophylactically and therapeutically against cutaneous herpesvirus infection of hairless mice. Activity was comparable to that obtained with adenine arabinoside.