Open AccessEvaluation of the Performance Parameters of a Prediluted, Quantitative Antibiotic Susceptibility Test Device
Author(s) -
Richard C. Tilton,
Henry D. Isenberg
Publication year - 1977
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.11.2.271
Subject(s) - antibiotics , penicillin , minocycline , clindamycin , ampicillin , erythromycin , tetracycline , microbiology and biotechnology , minimum inhibitory concentration , biology , medicine
A multiwelled plastic strip containing prediluted antibiotics was tested. Antibiotics available at the time of testing included ampicillin, penicillin, methicillin, erythromycin, clindamycin, tetracycline, and minocycline. The effects of inoculum size, inoculum volume, temperature, and time of incubation were determined. A limited clinical evaluation using laboratory strains of selected bacteria proved this product to be a rapid, economical, and reliable method for the determination of the minimal inhibitory concentration of antibiotics.