Open AccessTherapeutic Effects of Small-Particle Aerosols of Ribavirin on Parainfluenza (Sendai) Virus Infections of Mice
Author(s) -
E W Larson,
E. L. Stephen,
J. S. Walker
Publication year - 1976
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.10.4.770
Subject(s) - ribavirin , sendai virus , virology , virus , lung , paramyxoviridae , medicine , biology , viral disease , hepatitis c virus
Small-particle aerosol administration of ribavirin (1-beta-d-ribofuranosyl-1,2,4-triazole-3-carboxamide) increased survival rates, extended the time to death, delayed lung pathology, and reduced pulmonary virus levels in Sendai virus-infected mice.
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