Comparison of Thrombophlebitis Associated with Three Cephalosporin Antibiotics | Zendy

W. T. Siebert | Zendy; Eric L. Westerman | Zendy; Jerry D. Smilack | Zendy; Major W. Bradshaw | Zendy; Temple W. Williams | Zendy

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Comparison of Thrombophlebitis Associated with Three Cephalosporin Antibiotics

Author(s) -

W. T. Siebert,

Eric L. Westerman,

Jerry D. Smilack,

Major W. Bradshaw,

Temple W. Williams

Publication year - 1976

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.10.3.467

Subject(s) - thrombophlebitis , cephalosporin , medicine , cefamandole , incidence (geometry) , antibiotics , surgery , microbiology and biotechnology , thrombosis , biology , physics , optics

A double-blind study with volunteers was performed to determine the incidence and severity of thrombophlebitis associated with cephalothin, cephapirin, cefamandole, and a water control. Although there were no statistical differences in the incidence of thrombophlebitis, cephalothin resulted in significantly more severe thrombophlebitis compared with the other agents.

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