Open AccessIn Vitro Antimicrobial Resistance of Urinary Escherichia coli Isolates among U.S. Outpatients from 2000 to 2010
Author(s) -
Guillermo V. Sanchez,
Ronald N. Master,
James A. Karlowsky,
José Bordón
Publication year - 2012
Publication title -
antimicrobial agents and chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.07
H-Index - 259
eISSN - 1070-6283
pISSN - 0066-4804
DOI - 10.1128/aac.06060-11
Subject(s) - ciprofloxacin , nitrofurantoin , antimicrobial , escherichia coli , microbiology and biotechnology , sulfamethoxazole , trimethoprim , ceftriaxone , urine , antibiotic resistance , biology , medicine , antibiotics , gene , biochemistry
This study examinesin vitro antimicrobial resistance data fromEscherichia coli isolates obtained from urine samples of U.S. outpatients between 2000 and 2010 using The Surveillance Network (TSN). Antimicrobial susceptibility results (n = 12,253,679) showed the greatest increases inE. coli resistance from 2000 to 2010 for ciprofloxacin (3% to 17.1%) and trimethoprim-sulfamethoxazole (TMP-SMX) (17.9% to 24.2%), whereas nitrofurantoin (0.8% to 1.6%) and ceftriaxone (0.2% to 2.3%) showed minimal change. From 2000 to 2010, the antimicrobial resistance of urinaryE. coli isolates to ciprofloxacin and TMP-SMX among outpatients increased substantially.
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