Tn 125 -Related Acquisition of bla NDM -Like Genes in Acinetobacter baumannii | Zendy

Laurent Poirel | Zendy; Rémy A. Bonnin | Zendy; Anne Boulanger | Zendy; Jacques Schrenzel | Zendy; Martin Kaase | Zendy; Patrice Nordmann | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Tn 125 -Related Acquisition of bla _NDM -Like Genes in Acinetobacter baumannii

Author(s) -

Laurent Poirel,

Rémy A. Bonnin,

Anne Boulanger,

Jacques Schrenzel,

Martin Kaase,

Patrice Nordmann

Publication year - 2011

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.05620-11

Subject(s) - acinetobacter baumannii , transposable element , gene , biology , insertion sequence , plasmid , dna transposable elements , microbiology and biotechnology , genetics , multiple drug resistance , acinetobacter , drug resistance , genome , antibiotics , bacteria , pseudomonas aeruginosa

A multidrug-resistantAcinetobacter baumannii isolate recovered from a patient hospitalized in Switzerland after a transfer from Serbia produced the NDM-1 carbapenemase. Thebla NDM-1 gene was part of a chromosomally located Tn125 composite transposon bracketed by two copies of the same insertion sequence, ISAba125 . This transposon was also associated with the acquisition and expression of thebla NDM-2 gene in anA. baumannii isolate in Germany. Tn125 appears to be the main vehicle for dissemination ofbla NDM genes in that species.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research