ICE Sp2905 , the erm (TR)- tet (O) Element of Streptococcus pyogenes, Is Formed by Two Independent Integrative and Conjugative Elements | Zendy

Eleonora Giovanetti | Zendy; Andrea Brenciani | Zendy; Erika Tiberi | Zendy; Alessandro Bacciaglia | Zendy; Pietro E. Varaldo | Zendy

Open Access

ICE Sp2905 , the erm (TR)- tet (O) Element of Streptococcus pyogenes, Is Formed by Two Independent Integrative and Conjugative Elements

Author(s) -

Eleonora Giovanetti,

Andrea Brenciani,

Erika Tiberi,

Alessandro Bacciaglia,

Pietro E. Varaldo

Publication year - 2011

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.05352-11

Subject(s) - streptococcus pyogenes , element (criminal law) , microbiology and biotechnology , fragment (logic) , biology , genetics , chemistry , bacteria , computer science , staphylococcus aureus , political science , law , programming language

In ICESp2905 , a widespreaderm (TR)- andtet (O)-carrying genetic element ofStreptococcus pyogenes , the two resistance determinants are contained in separate fragments inserted into a scaffold of clostridial origin. ICESp2905 (∼65.6 kb) was transferable not only in its regular form but also in a defective form lacking theerm (TR) fragment (ICESp2906 , ∼53.0 kb). Theerm (TR) fragment was also an independent integrative and conjugative element (ICE) (ICESp2907 , ∼12.6 kb). ICESp2905 thus results from one ICE (ICESp2907 ) being integrated into another (ICESp2906 ).

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