Secular Trends Associated with Enterobacteriaceae with a Cefepime Susceptible-Dose-Dependent MIC | Zendy

Jamie L. Wagner | Zendy; Rachel M. Kenney | Zendy; Robert Tibbetts | Zendy; Susan L. Davis | Zendy

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Secular Trends Associated with Enterobacteriaceae with a Cefepime Susceptible-Dose-Dependent MIC

Author(s) -

Jamie L. Wagner,

Rachel M. Kenney,

Robert Tibbetts,

Susan L. Davis

Publication year - 2014

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.04491-14

Subject(s) - cefepime , enterobacteriaceae , enterobacteriaceae infections , secular variation , cephalosporin , microbiology and biotechnology , medicine , biology , antibiotics , antibiotic resistance , demography , genetics , escherichia coli , imipenem , gene , sociology

Cefepime, a fourth-generation, extended-spectrum cephalosporin, is often used to treat Enterobacteriaceae infections ([1][1]). Concentrations of cefepime above the MIC of the infecting organism for at least 60% to 70% of the dosing interval are recommended to obtain maximal bactericidal effects ([2

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