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Cefepime, a fourth-generation, extended-spectrum cephalosporin, is often used to treat Enterobacteriaceae infections ([1][1]). Concentrations of cefepime above the MIC of the infecting organism for at least 60% to 70% of the dosing interval are recommended to obtain maximal bactericidal effects ([2

Secular Trends Associated with Enterobacteriaceae with a Cefepime Susceptible-Dose-Dependent MIC