Molecular Characterization of Streptococcus agalactiae Isolates Harboring Small erm (T)-Carrying Plasmids | Zendy

Fabrice Compain | Zendy; Constantin Hays | Zendy; Gérald Touak | Zendy; Nicolas Dmytruk | Zendy; Patrick TrieuCuot | Zendy; Caroline Joubrel | Zendy; Claire Poyart | Zendy

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Molecular Characterization of Streptococcus agalactiae Isolates Harboring Small erm (T)-Carrying Plasmids

Author(s) -

Fabrice Compain,

Constantin Hays,

Gérald Touak,

Nicolas Dmytruk,

Patrick TrieuCuot,

Caroline Joubrel,

Claire Poyart

Publication year - 2014

Publication title -

antimicrobial agents and chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.07

H-Index - 259

eISSN - 1070-6283

pISSN - 0066-4804

DOI - 10.1128/aac.03855-14

Subject(s) - streptococcus agalactiae , microbiology and biotechnology , plasmid , enterococcus faecalis , erythromycin , streptococcaceae , biology , streptococcus , enterococcus , group b , gene , antibiotics , escherichia coli , bacteria , medicine , genetics

Among 1,827 group B Streptococcus (GBS) strains collected between 2006 and 2013 by the French National Reference Center for Streptococci, 490 (26.8%) strains were erythromycin resistant. The erm(T) resistance gene was found in six strains belonging to capsular polysaccharides Ia, III, and V and was carried by the same mobilizable plasmid, which could be efficiently transferred by mobilization to GBS and Enterococcus faecalis recipients, thus promoting a broad dissemination of erm(T).

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